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House Speaker Paul Ryan's decision to retire is throwing House Republicans into chaos at a time when the party is deeply worried about losing control of that chamber.

NPR's Audie Cornish speaks with Angela Kane, who was in charge of the chemical weapons investigation in Syria in 2013. They discuss what chemical watchdog inspectors will do when they get to Douma Saturday.

After dropping sharply when President Trump took office, the number of undocumented immigrants apprehended at the border is again on the rise.

When federal prosecutors served President Trump's personal lawyer — Michael Cohen — a warrant this week - one of the things on the list was Cohen's communications with a man named David J. Pecker, the publisher of the National Enquirer. NPR looks at why the special counsel might be interested in this communication.

As with Europe, the Trump administration is sending conflicting signals to America's long-standing allies in Asia, with whom the U.S. has deep-rooted security agreements that date back to the 1950s.

NPR's Mary Louise Kelly speaks with Sen. Chris Coons, D-Del., about the bipartisan bill he and his co-sponsors are introducing to protect Robert Mueller and other Special Counsels from being fired by the President.

A commission appointed to investigate the events leading up to and the response to the shooting in Parkland, Fla., began work Tuesday. Among the first areas of focus was the lack of coordination between law enforcement, which hampered their response to the shootings.

NPR's Mary Louise Kelly speaks with E.J. Dionne of the Washington Post and the Brookings Institution and Guy Benson of townhall.com about former FBI director James Comey's book, potential strikes on Syria and House Speaker Paul Ryan's announcement that he won't run for reelection.

Voters in Minnesota, Wisconsin, Vermont and Connecticut will decide the latest batch of primary elections Tuesday.

President Trump and the White House had stayed mostly silent in the wake of Paul Manafort's conviction and Michael Cohen's guilty plea, but Wednesday, he returned to Twitter and taped a TV interview.